110642 Determination of enoxacin and 4-oxo-enoxacin

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Determination of enoxacin and 4-oxo-enoxacin

Summary

Type: HPLC
Application #: 110642
Detection: UV 340 nm
Conditions: Eluents: acetonitrile buffer 20.9% (v/v), pH 2.1
Temperature: 25°C
Injection: 20 μl
Concentration:
(a) blank prostatic tissue; (b) prostatic tissue spiked with 625 ng/g of enoxacin and 4-oxo-enoxacin; (c) plasma of a patient treated with 400 mg of enoxacin twice a day (enoxacin: 6202 ng/g; 4-oxo-enoxacin: 509 ng/g)
Flow rate: 0.9 ml/min
Authors: Hamel B
Source: J Chromatogr A 812 (1998) 369-379