105080 Determination of denopamine in human and dog plasma by HPLC with electrochemical detection
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Determination of denopamine in human and dog plasma by HPLC with electrochemical detection
Summary
Type: HPLCApplication #: 105080
Catalog#: 720120.46 - MN HPLC Column, Nucleosil C18, 100A, 5um, 4.6x150mm
Detection: electrochemical, potential +750mV versus Ag/AgCl
Conditions: eluent: acetonitrile - 0.1M K2HPO4 (27:100, v/v), adjusted to pH 5.5 with o-phosphoric acid
flow rate 0.9ml/min
Authors: Tagawa, K. et al.
Source: J. Chromatogr. 529 (1990) 500–506
Details
Legend: Fig. 3. Chromatograms of denopamine in human plasma, A) blank plasma, B) plasma spiked with 20ng denopamine, C) plasma after oral administration of 10mg denopamine.