105060 Determination of metoclopramide in human plasma by HPLC

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Determination of metoclopramide in human plasma by HPLC

Summary

Type: HPLC
Application #: 105060
Catalog#: 720014.46 - MN HPLC Column, Nucleosil C18, 100A, 5um, 4.6x250mm
Detection: UV, 273nm
Conditions: eluent: 32% acetic acid (1%) and 68% acetonitrile - methanol (3.7:1, v/v)
flow rate 1.5ml/min
temperature 50°C
Authors: Bishop-Freudling GP
Source: J Chromatogr 273 (1983) 453 - 457


Details


Legend: Fig. 1. Chromatograms of extracts from A) drug-free control plasma and B) plasma sample obtained from a healthy volunteer 0.5h after taking a single oral dose of 20mg metoclopramide hydrochloride; t