105020 Determination of lansoprazole and its metabolites in plasma by HPLC using a loop column

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Determination of lansoprazole and its metabolites in plasma by HPLC using a loop column

Summary

Type: HPLC
Application #: 105020
Catalog#: 720014.46 - MN HPLC Column, Nucleosil C18, 100A, 5um, 4.6x250mm
Detection: UV, 285nm
Conditions: eluent: 360ml acetonitrile, 105ml phosphoric acid, 40ml 0.25M KH2PO4, 1.5ml triethylamine, 492ml water flow rate 2ml/min
Authors: Delhotal Landes, B.
Source: J. Chromatogr. 577 (1992) 117–122


Details


Legend: Fig. 2. a) Chromatogram of extracted blank plasma spiked with 50ng/ml each of metabolites I, II, III, IV and V and 100ng/ml lansoprazole. Fig. 3. b) Chromatogram of extracted plasma from a sample, t