105000 Pharmacokinetics of cimetidine and its sulphoxide metabolite during hemodialysis

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Pharmacokinetics of cimetidine and its sulphoxide metabolite during hemodialysis

Summary

Type: HPLC
Application #: 105000
Detection: UV, 228nm
Conditions: eluent: 0.067M K / Na phosphate buffer pH 6.0 containing 20g/l NaCl - methanol (85:15)
flow rate 1.2ml/min
Authors: Larsson R
Source: Eur J Clin Pharmacol 21 (1982) 325 - 330


Details


Legend: Fig. 1. Chromatogram of an extract of plasma, 1. cimetidine sulphoxide, 2. internal standard, 3. cimetidine (1. and 3. 2.0µg/ml).