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HPLC of Abbott-53385 in dog rat and human plasma
Summary
Type: HPLCApplication #: 104950
Catalog#: 720120.46 - MN HPLC Column, Nucleosil C18, 100A, 5um, 4.6x150mm
Detection: UV, 240nm
Conditions: eluent: methanol - acetonitrile - 85% phosphoric acid - water (40:18:0.2:41.8, v/v)
flow rate 1.0ml/min
Authors: Thomas EW
Source: J Liquid Chromatogr 9 (1986) 1479 - 1487
Details
Legend: Fig. 2. Chromatograms of A) extracted blank dog plasma, B) extracted dog plasma spiked with 0.5 µg/ml I (1) and internal standard (2), C) processed dog plasma, 0.5h post dosing of 0.3mg/kg I.