104750 Automated precolumn HPLC method for the investigation of adibendan metabolism

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Automated precolumn HPLC method for the investigation of adibendan metabolism

Summary

Type: HPLC
Application #: 104750
Catalog#: 720002.46 - MN HPLC Column, Nucleosil C18, 100A, 5um, 4.6x125mm
Detection: UV, 230nm
Conditions: eluent: 0.05M ammonium acetate buffer pH 3.5 - methanol (60:40, v/v)
flow rate 1ml/min
Authors: Neubert P
Source: J Chromatogr 490 (1989) 155 - 164


Details


Legend: Fig. 2. Metabolic profiling using precolumn HPLC. Analysis of 0 - 48h dog urine after oral administration of 1mg/kg 14Cadibendan, A) on-line sample cleanup from five consecutive precolumn injections