104540 HPLC Determination of Chlordiazepoxide its Metabolites and Oxaziridines Generated after UV Irradiation

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HPLC Determination of Chlordiazepoxide its Metabolites and Oxaziridines Generated after UV Irradiation

Summary

Type: HPLC
Application #: 104540
Catalog#: 720141.46 - MN HPLC Column, Nucleosil C18, 100A, 5um, 4.6x100mm
Detection: UV, 265nm
Conditions: CH3CN-THF-0.06 M phosphate buffer (pH 5.8) (22 : 2 : 76)
Column temperature: 20 °C
flow rate: 1.0 ml/min
Authors: Soentjens-Werts S
Source: J Chromatogr A 662 (1994) 255 - 262


Details


Legend: Fig. 4: HPLC separation of chlordiazoepoxide (4), its metabolites, namely desmethylCDZ (2), demoxepam (1), desmethyldiazepam (5) and oxazepam (3) and its photoproducts after UV irradiation for 70 mi