104070 Multiple peak formation in reversed phase liquid chromatography of ramipril and ramiprilate

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Multiple peak formation in reversed phase liquid chromatography of ramipril and ramiprilate

Summary

Type: HPLC
Application #: 104070
Detection: UV, 220nm
Conditions: column temperature: upper trace 30°C, lower trace 60°C, a lower temperature will improve resolution of the isomers
eluent: 30% acetonitrile in phosphate buffer pH 2
flow rate 1ml/min
Authors: Gustafsson S
Source: J Chromatogr 506 (1990) 75 - 83


Details


Legend: Fig. 7. Chromatograms of 1. ramiprilate and 2. ramipril.