104020 Determination of clonidine hydrochloride in pharmaceutical preparations by HPLC

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Determination of clonidine hydrochloride in pharmaceutical preparations by HPLC

Summary

Type: HPLC
Application #: 104020
Catalog#: 720002.46 - MN HPLC Column, Nucleosil C18, 100A, 5um, 4.6x125mm
Detection: UV, 240nm, attenuation a) 0.02 AUFS, b) 0.16 AUFS
Conditions: eluent: methanol - water - triethylamine (80:20:0.005)
flow rate 1ml/min
Authors: Wilczynska-Wojtulewicz I
Source: J Chromatogr 367 (1986) 434 - 437


Details


Legend: Fig. 1. Chromatograms of methanol - water extract of a) clonidine hydrochloride tablets and b) diluted eye drops. Concentration of CLH: a) ~ 4µg/ml, and b) ~ 25µg/ml.