103950 Measurement of maprotiline and oxaprotiline in plasma by HPLC of fluorescent derivatives

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Measurement of maprotiline and oxaprotiline in plasma by HPLC of fluorescent derivatives

Summary

Type: HPLC
Application #: 103950
Detection: fluorescence, excitation 365nm, emission 420nm
Conditions: eluent: hexane - abs. ethanol (95:5, v/v)
flow rate 1.8ml/min
Authors: Breyer-Pfaff U
Source: J Chromatogr 309 (1984) 107 - 114


Details


Legend: Fig. 1. HPLC fluorescence records obtained upon maprotiline analysis in 1ml plasma A) blank plasma B) blank plasma spiked with 10ng maprotiline and 400ng oxaprotiline (int. std.) C) plasma from a p