103650 Sensitive determination of josamycin and rokitamycin in plasma by HPLC with fluorescence detection

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Sensitive determination of josamycin and rokitamycin in plasma by HPLC with fluorescence detection

Summary

Type: HPLC
Application #: 103650
Catalog#: 720949.46 - MN HPLC Column, Nucleosil C18, 100A, 3um, 4.6x150mm
Detection: fluorescence, excitation 352nm, emission 537nm
Conditions: eluent: acetonitrile - 0.05M ammonium acetate (72:28, v/v)
flow rate 0.8ml/min
Authors: Tod M
Source: J Chromatogr 575 (1992) 171 - 176


Details


Legend: Fig. 2. Chromatograms of A) drug-free human plasma, B) 200ng/ml josamycin (9.7min) and 200ng/ml rokitamycin (11.6min) in human plasma and C) 21ng/ml rokitamycin in plasma from a patient 3h after a 4