103500 Stability and degradation pattern of cefpirome (HR 810) in aqueous solution

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Stability and degradation pattern of cefpirome (HR 810) in aqueous solution

Summary

Type: HPLC
Application #: 103500
Catalog#: 720023.40 - MN HPLC Column, Nucleosil C18, 100A, 10um, 4x250mm
Detection: UV
Conditions: eluent: 1% KH2PO4 - acetonitrile (8:1, v/v)
flow rate 1ml/min
Authors: Sugioka, T. et al.
Source: Chem. Pharm. Bull. 38 (1990) 1998–2002


Details


Legend: Fig. 3. Chromatograms of degraded cefpirome in aqueous solution of different pH values, (a) pH 1 (0.5N HCl), 40°C, 24h, (b) pH 3, 40°C, 24h, (c) pH 7, 40°C, 24h, (d) pH 8, 40°C, 24h (pH 3 - 8 McIvai