103370 Determination of rifampicin and its main metabolites in human plasma by HPLC

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Determination of rifampicin and its main metabolites in human plasma by HPLC

Summary

Type: HPLC
Application #: 103370
Catalog#: 720018.40 - MN HPLC Column, Nucleosil C18, 100A, 7um, 4x250mm
Detection: UV, 340nm
Conditions: eluent: acetonitrile - 0.1M KH2PO4, adjusted to pH 4.0 with 0.2M phosphoric acid (38:62, v/v) flow rate 1.2ml/min temperature: 40°C
Authors: Ishii, M.
Source: J. Chromatogr. 426 (1988) 412–416


Details


Legend: Fig. 1. Chromatogram of rifampicin (R), 25-deacetylrifampicin (DR), 3-formyl-25-deacetylrifamycin SV (FDR), 3-formylrifamycin SV (FR) and papaverine as internal standard (I.S.).