102940 Simultaneous determination of progabide and its acid metabolite by reversed phase HPLC

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Simultaneous determination of progabide and its acid metabolite by reversed phase HPLC

Summary

Type: HPLC
Application #: 102940
Catalog#: 720014.46 - MN HPLC Column, Nucleosil C18, 100A, 5um, 4.6x250mm
Detection: UV, 340nm
Conditions: eluent: 9g/ KH2PO4, 0.14g/l Na2HPO4 buffer pH 5.05 - methanol - acetonitrile - 0.15M NaCl (36:27:27:10)
flow rate 2.5ml/min
Authors: Decourt JP
Source: J Chromatogr 527 (1990) 214 - 219


Details


Legend: Fig. 2. Chromatograms of A) drug-free extract of plasma and B) sample containing 280ng/ml PG and 720ng/ml APG (acid progabide); 1. thiopental (int. std.), 2. APG, 3. PG.